Health condition

Amyotrophic Lateral Sclerosis

What is Amyotrophic Lateral Sclerosis?

A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)

Biomedical terminology and classification based on Medical Subject Headings (MeSH).

Research evidence

This condition is included in the encyclopedia, but no sufficiently linked research records are currently available in the local evidence database.

Most studied probiotic strains

Probiotic effects can be strain-specific. The organisms below are ranked using publications currently linked to this condition.

No specific probiotic strains are currently linked to this condition in the evidence database.

Key research

No highly relevant research articles are currently available for this condition in the local evidence database.

This encyclopedia page summarizes indexed biomedical research and terminology. Research associations do not establish diagnosis, treatment efficacy, or medical advice.