Strain

Lactobacillus rhamnosus GG

Lacticaseibacillus rhamnosus GG

497 Research articles
17 Conditions studied

Health overview

One of the most extensively studied probiotic strains worldwide.

Evidence summary

  • Research volume: 497 published studies
  • Health areas studied: Digestive health, immune function, inflammation, metabolic health and microbiome research
  • Research status: Clinical studies, reviews and meta-analyses are available. Effects depend on the specific species and strain.

Taxonomic classification

Lactobacillus → Lactobacillus rhamnosus → Lactobacillus rhamnosus GG

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Overview Evidence summary Research Publications Conditions Products Related microbes

Scientific classification

  • Type: strain
  • Strain: ATCC 53103
  • Taxonomic level: strain

Scientific background

Lactobacillus rhamnosus GG (LGG), also classified as Lacticaseibacillus rhamnosus GG, is a probiotic bacterial strain originally isolated from the human intestinal microbiota. It is identified by the strain designation ATCC 53103.

Mechanisms studied

Research has investigated several biological characteristics of LGG, including survival through gastrointestinal conditions, adhesion properties, interaction with intestinal epithelial cells, and communication with host immune pathways.

Research evidence

497 published studies connected to this microbe

Selected research publications

The effects of GG supplementation on gastrointestinal and respiratory outcomes: a systematic review and meta-analysis of randomized controlled trials.

Journal: Food & function

Year: 2025

Study type: Meta-analysis

View on PubMed

Systematic review and meta-analysis on probiotics as treatment for food allergies among pediatric patients: A 2024 update.

Journal: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology

Year: 2025

Study type: Meta-analysis

View on PubMed

Lactobacillus rhamnosus GG as a probiotic for preterm infants: a strain specific systematic review and meta-analysis.

Journal: European journal of clinical nutrition

Year: 2024

Study type: Meta-analysis

View on PubMed

A systematic review of the beneficial effects of prebiotics, probiotics, and synbiotics on ADHD.

Journal: Neuropsychopharmacology reports

Year: 2024

Study type: Systematic Review

View on PubMed

Probiotics for management of functional abdominal pain disorders in children.

Journal: The Cochrane database of systematic reviews

Year: 2023

Study type: Meta-analysis

View on PubMed

Conditions investigated

Inflammation 50 publications Allergy 39 publications Irritable bowel syndrome 23 publications Atopic dermatitis 23 publications Antibiotic-associated diarrhea 22 publications Inflammatory bowel disease 19 publications Eczema 19 publications Necrotizing enterocolitis 17 publications Constipation 14 publications Obesity 12 publications Ulcerative colitis 11 publications Infant colic 3 publications Clostridioides difficile infection 2 publications Type 2 diabetes 2 publications Immune health 2 publications Digestive Health 1 publications Metabolic Health 1 publications

Safety information

LGG is one of the best-characterized probiotic strains in scientific literature. Safety and effectiveness can depend on the population studied, dosage, formulation, and specific health context.

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